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Overexpression of GATA2 Enhances Development and Maintenance of Human Embryonic Stem Cell-Derived Hematopoietic Stem Cell-like Progenitors

GATA2 is essential for the endothelial-to-hematopoietic transition (EHT) and generation of hematopoietic stem cells (HSCs). It is poorly understood how GATA2 controls the development of human pluripotent stem cell (hPSC)-derived HS-like cells. Here, using human embryonic stem cells (hESCs) in which...

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Detalles Bibliográficos
Autores principales:	Zhou, Ya, Zhang, Yonggang, Chen, Bo, Dong, Yong, Zhang, Yimeng, Mao, Bin, Pan, Xu, Lai, Mowen, Chen, Yijin, Bian, Guohui, Zhou, Qiongxiu, Nakahata, Tatsutoshi, Zhou, Jiaxi, Wu, Min, Ma, Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6626852/ https://www.ncbi.nlm.nih.gov/pubmed/31178416 http://dx.doi.org/10.1016/j.stemcr.2019.05.007

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