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Frequency of germline mutations in BRCA1 and BRCA2 in ovarian cancer patients and their effect on treatment outcome

AIM OF WORK: Reporting the incidence and the variants of BRCA1/2 mutations in ovarian cancer patients exploring their effects on the treatment outcomes. PATIENTS AND METHODS: In total, 104 patients with epithelial ovarian cancer were prospectively recruited to the study. Analysis consisted of the se...

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Detalles Bibliográficos
Autores principales: Ashour, Mohamed, Ezzat Shafik, Hanan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6626894/
https://www.ncbi.nlm.nih.gov/pubmed/31372034
http://dx.doi.org/10.2147/CMAR.S206817