Cargando…
Anterior ischemic optic neuropathy in a patient with optic disc Drusen while on FOLFOX Chemotherapy for colon cancer: the value of Occam’s Razor and Hickam’s dictum
A 53-year-old male developed acute diminution of vision in his right eye while on FOLFOX chemotherapy for stage C colon cancer. Examination revealed bilateral optic nerve head swelling with flame shaped hemorrhages over the right optic disc and anomalous left retinal vasculature. Computed tomography...
Autor principal: | |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Romanian Society of Ophthalmology
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6626935/ https://www.ncbi.nlm.nih.gov/pubmed/31334397 |
_version_ | 1783434624998834176 |
---|---|
author | Elnahry, Gehad Ayman |
author_facet | Elnahry, Gehad Ayman |
author_sort | Elnahry, Gehad Ayman |
collection | PubMed |
description | A 53-year-old male developed acute diminution of vision in his right eye while on FOLFOX chemotherapy for stage C colon cancer. Examination revealed bilateral optic nerve head swelling with flame shaped hemorrhages over the right optic disc and anomalous left retinal vasculature. Computed tomography scan of the brain and orbit revealed no cerebral pathology, however bilateral optic disc drusen (ODD) was suspected. B scan ultrasonography confirmed the presence of bilateral ODD. Fluorescein angiography showed early hypofluorescence of the right optic disc with bilateral late disc staining and a diagnosis of right anterior ischemic optic neuropathy (AION) with bilateral ODD was made. A literature review was performed and possible mechanisms for the development of AION in this case were discussed. |
format | Online Article Text |
id | pubmed-6626935 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Romanian Society of Ophthalmology |
record_format | MEDLINE/PubMed |
spelling | pubmed-66269352019-07-22 Anterior ischemic optic neuropathy in a patient with optic disc Drusen while on FOLFOX Chemotherapy for colon cancer: the value of Occam’s Razor and Hickam’s dictum Elnahry, Gehad Ayman Rom J Ophthalmol Case Reports A 53-year-old male developed acute diminution of vision in his right eye while on FOLFOX chemotherapy for stage C colon cancer. Examination revealed bilateral optic nerve head swelling with flame shaped hemorrhages over the right optic disc and anomalous left retinal vasculature. Computed tomography scan of the brain and orbit revealed no cerebral pathology, however bilateral optic disc drusen (ODD) was suspected. B scan ultrasonography confirmed the presence of bilateral ODD. Fluorescein angiography showed early hypofluorescence of the right optic disc with bilateral late disc staining and a diagnosis of right anterior ischemic optic neuropathy (AION) with bilateral ODD was made. A literature review was performed and possible mechanisms for the development of AION in this case were discussed. Romanian Society of Ophthalmology 2019 /pmc/articles/PMC6626935/ /pubmed/31334397 Text en ©Romanian Society of Ophthalmology http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Reports Elnahry, Gehad Ayman Anterior ischemic optic neuropathy in a patient with optic disc Drusen while on FOLFOX Chemotherapy for colon cancer: the value of Occam’s Razor and Hickam’s dictum |
title | Anterior ischemic optic neuropathy in a patient with optic disc Drusen while on FOLFOX Chemotherapy for colon cancer: the value of Occam’s Razor and Hickam’s dictum
|
title_full | Anterior ischemic optic neuropathy in a patient with optic disc Drusen while on FOLFOX Chemotherapy for colon cancer: the value of Occam’s Razor and Hickam’s dictum
|
title_fullStr | Anterior ischemic optic neuropathy in a patient with optic disc Drusen while on FOLFOX Chemotherapy for colon cancer: the value of Occam’s Razor and Hickam’s dictum
|
title_full_unstemmed | Anterior ischemic optic neuropathy in a patient with optic disc Drusen while on FOLFOX Chemotherapy for colon cancer: the value of Occam’s Razor and Hickam’s dictum
|
title_short | Anterior ischemic optic neuropathy in a patient with optic disc Drusen while on FOLFOX Chemotherapy for colon cancer: the value of Occam’s Razor and Hickam’s dictum
|
title_sort | anterior ischemic optic neuropathy in a patient with optic disc drusen while on folfox chemotherapy for colon cancer: the value of occam’s razor and hickam’s dictum |
topic | Case Reports |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6626935/ https://www.ncbi.nlm.nih.gov/pubmed/31334397 |
work_keys_str_mv | AT elnahrygehadayman anteriorischemicopticneuropathyinapatientwithopticdiscdrusenwhileonfolfoxchemotherapyforcoloncancerthevalueofoccamsrazorandhickamsdictum |