“Switched” metabolic acidosis in mitochondrial diabetes mellitus

A patient with mitochondrial diabetes mellitus developed diabetic ketoacidosis. During insulin treatment, although diabetic ketoacidosis improved, lactic acidosis unexpectedly worsened. This clinical course, named “switched metabolic acidosis,” could reflect the unique pathophysiology of the mitocho...

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Detalles Bibliográficos
Autores principales: Keidai, Yamato, Iwasaki, Yorihiro, Honjo, Sachiko, Aizawa‐Abe, Megumi, Iwasaki, Kanako, Hamasaki, Akihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6626961/
https://www.ncbi.nlm.nih.gov/pubmed/30659759
http://dx.doi.org/10.1111/jdi.12992
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author Keidai, Yamato
Iwasaki, Yorihiro
Honjo, Sachiko
Aizawa‐Abe, Megumi
Iwasaki, Kanako
Hamasaki, Akihiro
author_facet Keidai, Yamato
Iwasaki, Yorihiro
Honjo, Sachiko
Aizawa‐Abe, Megumi
Iwasaki, Kanako
Hamasaki, Akihiro
author_sort Keidai, Yamato
collection PubMed
description A patient with mitochondrial diabetes mellitus developed diabetic ketoacidosis. During insulin treatment, although diabetic ketoacidosis improved, lactic acidosis unexpectedly worsened. This clinical course, named “switched metabolic acidosis,” could reflect the unique pathophysiology of the mitochondrial disorder.[Image: see text]
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spelling pubmed-66269612019-07-17 “Switched” metabolic acidosis in mitochondrial diabetes mellitus Keidai, Yamato Iwasaki, Yorihiro Honjo, Sachiko Aizawa‐Abe, Megumi Iwasaki, Kanako Hamasaki, Akihiro J Diabetes Investig Letter to the Editor A patient with mitochondrial diabetes mellitus developed diabetic ketoacidosis. During insulin treatment, although diabetic ketoacidosis improved, lactic acidosis unexpectedly worsened. This clinical course, named “switched metabolic acidosis,” could reflect the unique pathophysiology of the mitochondrial disorder.[Image: see text] John Wiley and Sons Inc. 2019-01-18 2019-07 /pmc/articles/PMC6626961/ /pubmed/30659759 http://dx.doi.org/10.1111/jdi.12992 Text en © 2019 The Authors. Journal of Diabetes Investigation published by Asian Association for the Study of Diabetes (AASD) and John Wiley & Sons Australia, Ltd This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Letter to the Editor
Keidai, Yamato
Iwasaki, Yorihiro
Honjo, Sachiko
Aizawa‐Abe, Megumi
Iwasaki, Kanako
Hamasaki, Akihiro
“Switched” metabolic acidosis in mitochondrial diabetes mellitus
title “Switched” metabolic acidosis in mitochondrial diabetes mellitus
title_full “Switched” metabolic acidosis in mitochondrial diabetes mellitus
title_fullStr “Switched” metabolic acidosis in mitochondrial diabetes mellitus
title_full_unstemmed “Switched” metabolic acidosis in mitochondrial diabetes mellitus
title_short “Switched” metabolic acidosis in mitochondrial diabetes mellitus
title_sort “switched” metabolic acidosis in mitochondrial diabetes mellitus
topic Letter to the Editor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6626961/
https://www.ncbi.nlm.nih.gov/pubmed/30659759
http://dx.doi.org/10.1111/jdi.12992
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