Rapid Irreversible Transcriptional Reprogramming in Human Stem Cells Accompanied by Discordance between Replication Timing and Chromatin Compartment

The temporal order of DNA replication is regulated during development and is highly correlated with gene expression, histone modifications and 3D genome architecture. We tracked changes in replication timing, gene expression, and chromatin conformation capture (Hi-C) A/B compartments over the first...

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Detalles Bibliográficos
Autores principales: Dileep, Vishnu, Wilson, Korey A., Marchal, Claire, Lyu, Xiaowen, Zhao, Peiyao A., Li, Ben, Poulet, Axel, Bartlett, Daniel A., Rivera-Mulia, Juan Carlos, Qin, Zhaohui S., Robins, Allan J., Schulz, Thomas C., Kulik, Michael J., McCord, Rachel Patton, Dekker, Job, Dalton, Stephen, Corces, Victor G., Gilbert, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627004/
https://www.ncbi.nlm.nih.gov/pubmed/31231024
http://dx.doi.org/10.1016/j.stemcr.2019.05.021

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