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Non-Invasive Monitoring of Stromal Biophysics with Targeted Depletion of Hyaluronan in Pancreatic Ductal Adenocarcinoma

Pancreatic ductal adenocarcinoma (PDA) is characterized by a pronounced fibroinflammatory stromal reaction consisting of inordinate levels of hyaluronan (HA), collagen, immune cells, and activated fibroblasts that work in concert to generate a robust physical barrier to the perfusion and diffusion o...

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Detalles Bibliográficos
Autores principales: Maloney, Ezekiel, DuFort, Christopher C., Provenzano, Paolo P., Farr, Navid, Carlson, Markus A., Vohra, Ravneet, Park, Joshua, Hingorani, Sunil R., Lee, Donghoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627077/
https://www.ncbi.nlm.nih.gov/pubmed/31167451
http://dx.doi.org/10.3390/cancers11060772

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