The Ubiquitin Proteasome System Is a Key Regulator of Pluripotent Stem Cell Survival and Motor Neuron Differentiation

The ubiquitin proteasome system (UPS) plays an important role in regulating numerous cellular processes, and a dysfunctional UPS is thought to contribute to motor neuron disease. Consequently, we sought to map the changing ubiquitome in human iPSCs during their pluripotent stage and following differ...

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Detalles Bibliográficos
Autores principales: Bax, Monique, McKenna, Jessie, Do-Ha, Dzung, Stevens, Claire H., Higginbottom, Sarah, Balez, Rachelle, Cabral-da-Silva, Mauricio e Castro, Farrawell, Natalie E., Engel, Martin, Poronnik, Philip, Yerbury, Justin J., Saunders, Darren N., Ooi, Lezanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627164/
https://www.ncbi.nlm.nih.gov/pubmed/31200561
http://dx.doi.org/10.3390/cells8060581

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627164/
https://www.ncbi.nlm.nih.gov/pubmed/31200561
http://dx.doi.org/10.3390/cells8060581

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