Cargando…
MMP-12, Secreted by Pro-Inflammatory Macrophages, Targets Endoglin in Human Macrophages and Endothelial Cells
Upon inflammation, monocyte-derived macrophages (MΦ) infiltrate blood vessels to regulate several processes involved in vascular pathophysiology. However, little is known about the mediators involved. Macrophage polarization is crucial for a fast and efficient initial response (GM-MΦ) and a good res...
Autores principales: | Aristorena, Mikel, Gallardo-Vara, Eunate, Vicen, Matej, de Las Casas-Engel, Mateo, Ojeda-Fernandez, Luisa, Nieto, Concepción, Blanco, Francisco J., Valbuena-Diez, Ana C., Botella, Luisa M., Nachtigal, Petr, Corbi, Angel L., Colmenares, María, Bernabeu, Carmelo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627183/ https://www.ncbi.nlm.nih.gov/pubmed/31242676 http://dx.doi.org/10.3390/ijms20123107 |
Ejemplares similares
-
Mice Lacking Endoglin in Macrophages Show an Impaired Immune Response
por: Ojeda-Fernández, Luisa, et al.
Publicado: (2016) -
Soluble endoglin regulates expression of angiogenesis-related proteins and induction of arteriovenous malformations in a mouse model of hereditary hemorrhagic telangiectasia
por: Gallardo-Vara, Eunate, et al.
Publicado: (2018) -
Transcription factor KLF6 upregulates expression of metalloprotease MMP14 and subsequent release of soluble endoglin during vascular injury
por: Gallardo-Vara, Eunate, et al.
Publicado: (2016) -
Endoglin (CD105) and VEGF as potential angiogenic and dissemination markers for colorectal cancer
por: Nogués, Ana, et al.
Publicado: (2020) -
Structural and Functional Insights into Endoglin Ligand Recognition and Binding
por: Alt, Aaron, et al.
Publicado: (2012)