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An Fc-Optimized CD133 Antibody for Induction of Natural Killer Cell Reactivity Against Colorectal Cancer

The introduction of monoclonal antibodies (mAbs) has largely improved treatment options for cancer patients. The ability of antitumor mAbs to elicit antibody-dependent cellular cytotoxicity (ADCC) contributes to a large extent to their therapeutic efficacy. Many efforts accordingly aim to improve th...

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Detalles Bibliográficos
Autores principales: Schmied, Bastian J., Riegg, Fabian, Zekri, Latifa, Grosse-Hovest, Ludger, Bühring, Hans-Jörg, Jung, Gundram, Salih, Helmut R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627285/
https://www.ncbi.nlm.nih.gov/pubmed/31181683
http://dx.doi.org/10.3390/cancers11060789