Dysbiosis and Prematurity: Is There a Role for Probiotics?

Healthy microbiota is a critical mediator in maintaining health and it is supposed that dysbiosis could have a role in the pathogenesis of a number of diseases. Evidence supports the hypothesis that maternal dysbiosis could act as a trigger for preterm birth; aberrant colonization of preterm infant...

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Autores principales: Baldassarre, Maria Elisabetta, Di Mauro, Antonio, Capozza, Manuela, Rizzo, Valentina, Schettini, Federico, Panza, Raffaella, Laforgia, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627287/
https://www.ncbi.nlm.nih.gov/pubmed/31195600
http://dx.doi.org/10.3390/nu11061273
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author Baldassarre, Maria Elisabetta
Di Mauro, Antonio
Capozza, Manuela
Rizzo, Valentina
Schettini, Federico
Panza, Raffaella
Laforgia, Nicola
author_facet Baldassarre, Maria Elisabetta
Di Mauro, Antonio
Capozza, Manuela
Rizzo, Valentina
Schettini, Federico
Panza, Raffaella
Laforgia, Nicola
author_sort Baldassarre, Maria Elisabetta
collection PubMed
description Healthy microbiota is a critical mediator in maintaining health and it is supposed that dysbiosis could have a role in the pathogenesis of a number of diseases. Evidence supports the hypothesis that maternal dysbiosis could act as a trigger for preterm birth; aberrant colonization of preterm infant gut might have a role in feeding intolerance and pathogenesis of necrotizing enterocolitis. Despite several clinical trials and meta-analyses, it is still not clear if modulation of maternal and neonatal microbiota with probiotic supplementation decreases the risk of preterm birth and its complications.
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spelling pubmed-66272872019-07-23 Dysbiosis and Prematurity: Is There a Role for Probiotics? Baldassarre, Maria Elisabetta Di Mauro, Antonio Capozza, Manuela Rizzo, Valentina Schettini, Federico Panza, Raffaella Laforgia, Nicola Nutrients Communication Healthy microbiota is a critical mediator in maintaining health and it is supposed that dysbiosis could have a role in the pathogenesis of a number of diseases. Evidence supports the hypothesis that maternal dysbiosis could act as a trigger for preterm birth; aberrant colonization of preterm infant gut might have a role in feeding intolerance and pathogenesis of necrotizing enterocolitis. Despite several clinical trials and meta-analyses, it is still not clear if modulation of maternal and neonatal microbiota with probiotic supplementation decreases the risk of preterm birth and its complications. MDPI 2019-06-05 /pmc/articles/PMC6627287/ /pubmed/31195600 http://dx.doi.org/10.3390/nu11061273 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Baldassarre, Maria Elisabetta
Di Mauro, Antonio
Capozza, Manuela
Rizzo, Valentina
Schettini, Federico
Panza, Raffaella
Laforgia, Nicola
Dysbiosis and Prematurity: Is There a Role for Probiotics?
title Dysbiosis and Prematurity: Is There a Role for Probiotics?
title_full Dysbiosis and Prematurity: Is There a Role for Probiotics?
title_fullStr Dysbiosis and Prematurity: Is There a Role for Probiotics?
title_full_unstemmed Dysbiosis and Prematurity: Is There a Role for Probiotics?
title_short Dysbiosis and Prematurity: Is There a Role for Probiotics?
title_sort dysbiosis and prematurity: is there a role for probiotics?
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627287/
https://www.ncbi.nlm.nih.gov/pubmed/31195600
http://dx.doi.org/10.3390/nu11061273
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