Cargando…

Marine-Derived Anticancer Agents: Clinical Benefits, Innovative Mechanisms, and New Targets

The role of the marine environment in the development of anticancer drugs has been widely reviewed, particularly in recent years. However, the innovation in terms of clinical benefits has not been duly emphasized, although there are important breakthroughs associated with the use of marine-derived a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pereira, Renato B., Evdokimov, Nikolai M., Lefranc, Florence, Valentão, Patrícia, Kornienko, Alexander, Pereira, David M., Andrade, Paula B., Gomes, Nelson G. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627313/ https://www.ncbi.nlm.nih.gov/pubmed/31159480 http://dx.doi.org/10.3390/md17060329

Ejemplares similares

Double the Chemistry, Double the Fun: Structural Diversity and Biological Activity of Marine-Derived Diketopiperazine Dimers
por: Gomes, Nelson G. M., et al.
Publicado: (2019)

Can Some Marine-Derived Fungal Metabolites Become Actual Anticancer Agents?
por: Gomes, Nelson G. M., et al.
Publicado: (2015)

Marine Mollusk‐Derived Agents with Antiproliferative Activity as Promising Anticancer Agents to Overcome Chemotherapy Resistance
por: Ciavatta, Maria Letizia, et al.
Publicado: (2016)

Nano- and Microdelivery Systems for Marine Bioactive Lipids
por: Pereira, David M., et al.
Publicado: (2014)

Marine Invertebrate Metabolites with Anticancer Activities: Solutions to the “Supply Problem”
por: Gomes, Nelson G. M., et al.
Publicado: (2016)

Chemical Diversity and Biological Properties of Secondary Metabolites from Sea Hares of Aplysia Genus
por: Pereira, Renato B., et al.
Publicado: (2016)

Bioactive Marine Drugs and Marine Biomaterials for Brain Diseases
por: Grosso, Clara, et al.
Publicado: (2014)

Alternative and Efficient Extraction Methods for Marine-Derived Compounds
por: Grosso, Clara, et al.
Publicado: (2015)

Tuning protein folding in lysosomal storage diseases: the chemistry behind pharmacological chaperones
por: Pereira, David M., et al.
Publicado: (2018)

Glutathione and the Antioxidant Potential of Binary Mixtures with Flavonoids: Synergisms and Antagonisms
por: Pereira, Renato B., et al.
Publicado: (2013)

Phenolics: From Chemistry to Biology
por: Pereira, David M., et al.
Publicado: (2009)

Pyrrolizidine Alkaloids: Chemistry, Pharmacology, Toxicology and Food Safety
por: Moreira, Rute, et al.
Publicado: (2018)

A Survey of Naturally Occurring Molecules as New Endoplasmic Reticulum Stress Activators with Selective Anticancer Activity
por: Correia da Silva, Daniela, et al.
Publicado: (2022)

Profiling of Heterobranchia Sea Slugs from Portuguese Coastal Waters as Producers of Anti-Cancer and Anti-Inflammatory Agents
por: Gomes, Nelson G. M., et al.
Publicado: (2018)

Flavonoid Composition of Salacia senegalensis (Lam.) DC. Leaves, Evaluation of Antidermatophytic Effects, and Potential Amelioration of the Associated Inflammatory Response
por: Gomes, Nelson G. M., et al.
Publicado: (2019)

A Pipeline for Natural Small Molecule Inhibitors of Endoplasmic Reticulum Stress
por: Correia da Silva, Daniela, et al.
Publicado: (2022)

Anti-Inflammatory Effects of 5α,8α-Epidioxycholest-6-en-3β-ol, a Steroidal Endoperoxide Isolated from Aplysia depilans, Based on Bioguided Fractionation and NMR Analysis
por: Pereira, Renato B., et al.
Publicado: (2019)

Marine Natural Products as Anticancer Agents
por: Alves, Celso, et al.
Publicado: (2021)

Phenolic Profiling and Biological Potential of Ficus curtipes Corner Leaves and Stem Bark: 5-Lipoxygenase Inhibition and Interference with NO Levels in LPS-Stimulated RAW 264.7 Macrophages
por: Andrade, Catarina, et al.
Publicado: (2019)

Anti-Inflammatory Effect of Unsaturated Fatty Acids and Ergosta-7,22-dien-3-ol from Marthasterias glacialis: Prevention of CHOP-Mediated ER-Stress and NF-κB Activation
por: Pereira, David M., et al.
Publicado: (2014)

Palmitic Acid and Ergosta-7,22-dien-3-ol Contribute to the Apoptotic Effect and Cell Cycle Arrest of an Extract from Marthasterias glacialis L. in Neuroblastoma Cells
por: Pereira, David M., et al.
Publicado: (2013)

Insights into Natural Products in Inflammation
por: Andrade, Paula B., et al.
Publicado: (2018)

Inhibition of Proinflammatory Enzymes and Attenuation of IL-6 in LPS-Challenged RAW 264.7 Macrophages Substantiates the Ethnomedicinal Use of the Herbal Drug Homalium bhamoense Cubitt & W.W.Sm
por: Suksungworn, Rungcharn, et al.
Publicado: (2020)

Further Insights on the Carotenoid Profile of the Echinoderm Marthasterias glacialis L
por: Mariutti, Lilian R. B., et al.
Publicado: (2012)

Therapeutic Properties and Biological Benefits of Marine-Derived Anticancer Peptides
por: Kang, Hee Kyoung, et al.
Publicado: (2018)

Fucoidan as a Marine Anticancer Agent in Preclinical Development
por: Kwak, Jong-Young
Publicado: (2014)

Marine Natural Products as Anticancer Agents 2.0
por: Alves, Celso, et al.
Publicado: (2023)

Novel Marine Secondary Metabolites Worthy of Development as Anticancer Agents: A Review
por: Mbaoji, Florence Nwakaego, et al.
Publicado: (2021)

Bioactive Compounds from Macroalgae in the New Millennium: Implications for Neurodegenerative Diseases
por: Barbosa, Mariana, et al.
Publicado: (2014)

Biologically Active Oxylipins from Enzymatic and Nonenzymatic Routes in Macroalgae
por: Barbosa, Mariana, et al.
Publicado: (2016)

Phlorotannins: Towards New Pharmacological Interventions for Diabetes Mellitus Type 2
por: Lopes, Graciliana, et al.
Publicado: (2016)

Polyphenols from Brown Seaweeds (Ochrophyta, Phaeophyceae): Phlorotannins in the Pursuit of Natural Alternatives to Tackle Neurodegeneration
por: Barbosa, Mariana, et al.
Publicado: (2020)

Kale Extract Increases Glutathione Levels in V79 Cells, but Does not Protect Them Against Acute Toxicity Induced by Hydrogen Peroxide
por: Fernandes, Fátima, et al.
Publicado: (2012)

Biological Evaluation of Naproxen–Dehydrodipeptide Conjugates with Self-Hydrogelation Capacity as Dual LOX/COX Inhibitors
por: Moreira, Rute, et al.
Publicado: (2020)

Adding pharmacogenomics to the development of new marine-derived anticancer agents
por: Jimeno, José, et al.
Publicado: (2006)

Synthesis of Marine Cyclopeptide Galaxamide Analogues as Potential Anticancer Agents
por: Li, Daichun, et al.
Publicado: (2022)

Anti-Proliferative Activity of Meroditerpenoids Isolated from the Brown Alga Stypopodium flabelliforme against Several Cancer Cell Lines
por: Pereira, David M., et al.
Publicado: (2011)

Antifungal Activity of Phlorotannins against Dermatophytes and Yeasts: Approaches to the Mechanism of Action and Influence on Candida albicans Virulence Factor
por: Lopes, Graciliana, et al.
Publicado: (2013)

Magnetic Dehydrodipeptide-Based Self-Assembled Hydrogels for Theragnostic Applications
por: Carvalho, André, et al.
Publicado: (2019)

Marine Anticancer Agents: An Overview with a Particular Focus on Their Chemical Classes
por: Barreca, Marilia, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_8008hr6ar1tqg454eg3aj3isvk