Nodal Facilitates Differentiation of Fibroblasts to Cancer-Associated Fibroblasts that Support Tumor Growth in Melanoma and Colorectal Cancer

Fibroblasts become cancer-associated fibroblasts (CAFs) in the tumor microenvironment after activation by transforming growth factor-β (TGF-β) and are critically involved in cancer progression. However, it is unknown whether the TGF superfamily member Nodal, which is expressed in various tumors but...

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Detalles Bibliográficos
Autores principales: Li, Ziqian, Zhang, Junjie, Zhou, Jiawang, Lu, Linlin, Wang, Hongsheng, Zhang, Ge, Wan, Guohui, Cai, Shaohui, Du, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627322/
https://www.ncbi.nlm.nih.gov/pubmed/31167491
http://dx.doi.org/10.3390/cells8060538

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