Cargando…
Identification of Small Molecule Inhibitors of Staphylococcus aureus RnpA
Staphylococcus aureus RnpA is thought to be a unique dual functional antimicrobial target that is required for two essential cellular processes, precursor tRNA processing and messenger RNA degradation. Herein, we used a previously described whole cell-based mupirocin synergy assay to screen members...
Autores principales: | Colquhoun, Jennifer M., Ha, Lisha, Beckley, Andrew, Meyers, Brinkley, Flaherty, Daniel P., Dunman, Paul M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627331/ https://www.ncbi.nlm.nih.gov/pubmed/31035380 http://dx.doi.org/10.3390/antibiotics8020048 |
Ejemplares similares
-
Optimization of 2-Acylaminocycloalkylthiophene Derivatives for Activity against Staphylococcus aureus RnpA
por: Chojnacki, Michaelle, et al.
Publicado: (2021) -
Staphylococcus aureus RnpA Inhibitors: Computational-Guided Design, Synthesis and Initial Biological Evaluation
por: Suigo, Lorenzo, et al.
Publicado: (2021) -
Small Molecule Inhibitors of Staphylococcus aureus RnpA Alter Cellular mRNA Turnover, Exhibit Antimicrobial Activity, and Attenuate Pathogenesis
por: Olson, Patrick D., et al.
Publicado: (2011) -
Repurposing the Antihistamine Terfenadine for Antimicrobial
Activity against Staphylococcus aureus
por: Perlmutter, Jessamyn I., et al.
Publicado: (2014) -
Identification of Small Molecule Inhibitors against Staphylococcus aureus Dihydroorotase via HTS
por: Rice, Amy J., et al.
Publicado: (2021)