Tunicate Heparan Sulfate Enriched in 2-Sulfated β-Glucuronic Acid: Structure, Anticoagulant Activity, and Inhibitory Effect on the Binding of Human Colon Adenocarcinoma Cells to Immobilized P-Selectin

Heparin or highly sulfated heparan sulfate (HS) has been described in different invertebrates. In ascidians (Chordata-Tunicata), these glycosaminoglycans occur in intracellular granules of oocyte accessory cells and circulating basophil-like cells, resembling mammalian mast cells and basophils, resp...

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Detalles Bibliográficos
Autores principales: Abreu, Wallace S., Soares, Paulo A. G., Motta, Juliana M., Kozlowski, Eliene O., Teixeira, Felipe C. O. B., Soares, Mariana A., Borsig, Lubor, Mourão, Paulo A. S., Pavão, Mauro S. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627333/
https://www.ncbi.nlm.nih.gov/pubmed/31212795
http://dx.doi.org/10.3390/md17060351

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