Hexokinase 2 Regulates Ovarian Cancer Cell Migration, Invasion and Stemness via FAK/ERK1/2/MMP9/NANOG/SOX9 Signaling Cascades

Metabolic reprogramming is a common phenomenon in cancers. Thus, glycolytic enzymes could be exploited to selectively target cancer cells in cancer therapy. Hexokinase 2 (HK2) converts glucose to glucose-6-phosphate, the first committed step in glucose metabolism. Here, we demonstrated that HK2 was...

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Detalles Bibliográficos
Autores principales: Siu, Michelle K. Y., Jiang, Yu-Xin, Wang, Jing-Jing, Leung, Thomas H. Y., Han, Chae Young, Tsang, Benjamin K., Cheung, Annie N. Y., Ngan, Hextan Y. S., Chan, Karen K. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627345/
https://www.ncbi.nlm.nih.gov/pubmed/31212816
http://dx.doi.org/10.3390/cancers11060813

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627345/
https://www.ncbi.nlm.nih.gov/pubmed/31212816
http://dx.doi.org/10.3390/cancers11060813

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