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Evaluation of Antibiotics Residues in Chicken Meat Samples in Lebanon

Antibiotic residue in chicken is a human health concern due to its harmful effects on consumer health. This study aims at screening the antibiotic residues from 80 chicken samples collected from farms located in different regions of Lebanon. An optimized multi-class method for identification and qua...

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Autores principales: Jammoul, Adla, El Darra, Nada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627442/
https://www.ncbi.nlm.nih.gov/pubmed/31141997
http://dx.doi.org/10.3390/antibiotics8020069
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author Jammoul, Adla
El Darra, Nada
author_facet Jammoul, Adla
El Darra, Nada
author_sort Jammoul, Adla
collection PubMed
description Antibiotic residue in chicken is a human health concern due to its harmful effects on consumer health. This study aims at screening the antibiotic residues from 80 chicken samples collected from farms located in different regions of Lebanon. An optimized multi-class method for identification and quantification of 30 antibiotics from four different chemical classes (sulfonamides, tetracyclines, quinolones, and beta-lactams) has been developed by using liquid chromatography–mass spectrometry. The evaluation of antibiotics residues in 80 chicken muscles samples has shown that 77.5% of samples were at least contaminated with antibiotics residues, out of which 53.75% were exposed to co-occurrence of multidrug residues. The screening of the four antibiotics families has shown that ciprofloxacin (quinolones) represents the highest occurrence percentage (32.5%), followed by amoxicillin (β-lactams) (22.5%) and then tetracyclines (17.5%). Means of sarafloxacin, amoxicillin, and penicillin G residues levels were above the Maximum Residue Limit (MRL) recommended limit according to the European Union EC. This study revealed that chicken samples collected from Lebanese farms contain antibiotic residues. Guidelines for prudent use of antimicrobials agents for chicken should be adopted to reduce the prevalence of resistant Salmonella in chicken.
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spelling pubmed-66274422019-07-23 Evaluation of Antibiotics Residues in Chicken Meat Samples in Lebanon Jammoul, Adla El Darra, Nada Antibiotics (Basel) Article Antibiotic residue in chicken is a human health concern due to its harmful effects on consumer health. This study aims at screening the antibiotic residues from 80 chicken samples collected from farms located in different regions of Lebanon. An optimized multi-class method for identification and quantification of 30 antibiotics from four different chemical classes (sulfonamides, tetracyclines, quinolones, and beta-lactams) has been developed by using liquid chromatography–mass spectrometry. The evaluation of antibiotics residues in 80 chicken muscles samples has shown that 77.5% of samples were at least contaminated with antibiotics residues, out of which 53.75% were exposed to co-occurrence of multidrug residues. The screening of the four antibiotics families has shown that ciprofloxacin (quinolones) represents the highest occurrence percentage (32.5%), followed by amoxicillin (β-lactams) (22.5%) and then tetracyclines (17.5%). Means of sarafloxacin, amoxicillin, and penicillin G residues levels were above the Maximum Residue Limit (MRL) recommended limit according to the European Union EC. This study revealed that chicken samples collected from Lebanese farms contain antibiotic residues. Guidelines for prudent use of antimicrobials agents for chicken should be adopted to reduce the prevalence of resistant Salmonella in chicken. MDPI 2019-05-28 /pmc/articles/PMC6627442/ /pubmed/31141997 http://dx.doi.org/10.3390/antibiotics8020069 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Jammoul, Adla
El Darra, Nada
Evaluation of Antibiotics Residues in Chicken Meat Samples in Lebanon
title Evaluation of Antibiotics Residues in Chicken Meat Samples in Lebanon
title_full Evaluation of Antibiotics Residues in Chicken Meat Samples in Lebanon
title_fullStr Evaluation of Antibiotics Residues in Chicken Meat Samples in Lebanon
title_full_unstemmed Evaluation of Antibiotics Residues in Chicken Meat Samples in Lebanon
title_short Evaluation of Antibiotics Residues in Chicken Meat Samples in Lebanon
title_sort evaluation of antibiotics residues in chicken meat samples in lebanon
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627442/
https://www.ncbi.nlm.nih.gov/pubmed/31141997
http://dx.doi.org/10.3390/antibiotics8020069
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