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Aberrant DNA Polymerase Beta Enhances H. pylori Infection Induced Genomic Instability and Gastric Carcinogenesis in Mice

H. pylori is a significant risk factor of gastric cancer that induces chronic inflammation and oxidative DNA damage to promote gastric carcinoma. Base excision repair (BER) is required to maintain the genome integrity and prevent oxidative DNA damage. Mutation in DNA polymerase beta (Pol β) impacts...

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Detalles Bibliográficos
Autores principales:	Zhao, Shengyuan, Thakur, Megha, Klattenhoff, Alex W., Kidane, Dawit
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627457/ https://www.ncbi.nlm.nih.gov/pubmed/31216714 http://dx.doi.org/10.3390/cancers11060843

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