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Oncogenic BRAF Alterations and Their Role in Brain Tumors

Alterations of the v-raf murine sarcoma viral oncogene homolog B (BRAF) have been extensively studied in several tumor entities and are known to drive cell growth in several tumor entities. Effective targeted therapies with mutation-specific small molecule inhibitors have been developed and establis...

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Detalles Bibliográficos
Autores principales: Behling, Felix, Schittenhelm, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627484/
https://www.ncbi.nlm.nih.gov/pubmed/31181803
http://dx.doi.org/10.3390/cancers11060794

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