Cargando…
Prevalence of Methicillin-Resistant Staphylococcus sp. (MRS) in Different Companion Animals and Determination of Risk Factors for Colonization with MRS
The aim of this study was to detect the prevalence of methicillin-resistant Staphylococcus sp. (MRS) in populations of companion animals that either have previously been exposed or have not been exposed to antibiotic therapy or veterinary facilities, and if owners’ healthcare profession had an influ...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627599/ https://www.ncbi.nlm.nih.gov/pubmed/30959767 http://dx.doi.org/10.3390/antibiotics8020036 |
_version_ | 1783434774166110208 |
---|---|
author | Loncaric, Igor Tichy, Alexander Handler, Silvia Szostak, Michael P. Tickert, Mareike Diab-Elschahawi, Magda Spergser, Joachim Künzel, Frank |
author_facet | Loncaric, Igor Tichy, Alexander Handler, Silvia Szostak, Michael P. Tickert, Mareike Diab-Elschahawi, Magda Spergser, Joachim Künzel, Frank |
author_sort | Loncaric, Igor |
collection | PubMed |
description | The aim of this study was to detect the prevalence of methicillin-resistant Staphylococcus sp. (MRS) in populations of companion animals that either have previously been exposed or have not been exposed to antibiotic therapy or veterinary facilities, and if owners’ healthcare profession had an influence on colonization with MRS. In addition, the antimicrobial resistance pheno- and genotype were investigated and risks for colonization with MRS were assessed. During this study, 347 nasal swabs (dogs n = 152; cats n = 107; rabbits n = 88) were investigated for the presence of methicillin-resistant Staphylococcus aureus (MRSA). In addition, 131 nasal swabs (dogs n = 79; cats n = 47; rabbits = 3; guinea pigs = 2) were examined for the presence of MRSA but also other MRS. In total, 23 MRS isolates belonged to nine staphylococcal species: Staphylococcus epidermidis (n = 11), Staphylococcus warneri (n = 3), Staphylococcus hominis (n = 2), Staphylococcus pseudintermedius (n = 2), and singletons Staphylococcus cohnii, Staphylococcus sciuri, Staphylococcus fleurettii, Staphylococcus lentus, and Staphylococcus haemolyticus. Twenty isolates displayed a multidrug-resistant phenotype. Various resistance and biocide resistance genes were detected among the examined staphylococci. Risk assessment for MRS colonization was conducted using a number of factors, including animal species, breed, age, gender, recent veterinary health care hospitalization, and antibiotic prescription, resulting in recent veterinary health care hospitalization being a significant risk factor. The detection of multidrug-resistant MRS in healthy animals is of importance due to their zoonotic potential. |
format | Online Article Text |
id | pubmed-6627599 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-66275992019-07-23 Prevalence of Methicillin-Resistant Staphylococcus sp. (MRS) in Different Companion Animals and Determination of Risk Factors for Colonization with MRS Loncaric, Igor Tichy, Alexander Handler, Silvia Szostak, Michael P. Tickert, Mareike Diab-Elschahawi, Magda Spergser, Joachim Künzel, Frank Antibiotics (Basel) Article The aim of this study was to detect the prevalence of methicillin-resistant Staphylococcus sp. (MRS) in populations of companion animals that either have previously been exposed or have not been exposed to antibiotic therapy or veterinary facilities, and if owners’ healthcare profession had an influence on colonization with MRS. In addition, the antimicrobial resistance pheno- and genotype were investigated and risks for colonization with MRS were assessed. During this study, 347 nasal swabs (dogs n = 152; cats n = 107; rabbits n = 88) were investigated for the presence of methicillin-resistant Staphylococcus aureus (MRSA). In addition, 131 nasal swabs (dogs n = 79; cats n = 47; rabbits = 3; guinea pigs = 2) were examined for the presence of MRSA but also other MRS. In total, 23 MRS isolates belonged to nine staphylococcal species: Staphylococcus epidermidis (n = 11), Staphylococcus warneri (n = 3), Staphylococcus hominis (n = 2), Staphylococcus pseudintermedius (n = 2), and singletons Staphylococcus cohnii, Staphylococcus sciuri, Staphylococcus fleurettii, Staphylococcus lentus, and Staphylococcus haemolyticus. Twenty isolates displayed a multidrug-resistant phenotype. Various resistance and biocide resistance genes were detected among the examined staphylococci. Risk assessment for MRS colonization was conducted using a number of factors, including animal species, breed, age, gender, recent veterinary health care hospitalization, and antibiotic prescription, resulting in recent veterinary health care hospitalization being a significant risk factor. The detection of multidrug-resistant MRS in healthy animals is of importance due to their zoonotic potential. MDPI 2019-04-05 /pmc/articles/PMC6627599/ /pubmed/30959767 http://dx.doi.org/10.3390/antibiotics8020036 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Loncaric, Igor Tichy, Alexander Handler, Silvia Szostak, Michael P. Tickert, Mareike Diab-Elschahawi, Magda Spergser, Joachim Künzel, Frank Prevalence of Methicillin-Resistant Staphylococcus sp. (MRS) in Different Companion Animals and Determination of Risk Factors for Colonization with MRS |
title | Prevalence of Methicillin-Resistant Staphylococcus sp. (MRS) in Different Companion Animals and Determination of Risk Factors for Colonization with MRS |
title_full | Prevalence of Methicillin-Resistant Staphylococcus sp. (MRS) in Different Companion Animals and Determination of Risk Factors for Colonization with MRS |
title_fullStr | Prevalence of Methicillin-Resistant Staphylococcus sp. (MRS) in Different Companion Animals and Determination of Risk Factors for Colonization with MRS |
title_full_unstemmed | Prevalence of Methicillin-Resistant Staphylococcus sp. (MRS) in Different Companion Animals and Determination of Risk Factors for Colonization with MRS |
title_short | Prevalence of Methicillin-Resistant Staphylococcus sp. (MRS) in Different Companion Animals and Determination of Risk Factors for Colonization with MRS |
title_sort | prevalence of methicillin-resistant staphylococcus sp. (mrs) in different companion animals and determination of risk factors for colonization with mrs |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627599/ https://www.ncbi.nlm.nih.gov/pubmed/30959767 http://dx.doi.org/10.3390/antibiotics8020036 |
work_keys_str_mv | AT loncaricigor prevalenceofmethicillinresistantstaphylococcusspmrsindifferentcompanionanimalsanddeterminationofriskfactorsforcolonizationwithmrs AT tichyalexander prevalenceofmethicillinresistantstaphylococcusspmrsindifferentcompanionanimalsanddeterminationofriskfactorsforcolonizationwithmrs AT handlersilvia prevalenceofmethicillinresistantstaphylococcusspmrsindifferentcompanionanimalsanddeterminationofriskfactorsforcolonizationwithmrs AT szostakmichaelp prevalenceofmethicillinresistantstaphylococcusspmrsindifferentcompanionanimalsanddeterminationofriskfactorsforcolonizationwithmrs AT tickertmareike prevalenceofmethicillinresistantstaphylococcusspmrsindifferentcompanionanimalsanddeterminationofriskfactorsforcolonizationwithmrs AT diabelschahawimagda prevalenceofmethicillinresistantstaphylococcusspmrsindifferentcompanionanimalsanddeterminationofriskfactorsforcolonizationwithmrs AT spergserjoachim prevalenceofmethicillinresistantstaphylococcusspmrsindifferentcompanionanimalsanddeterminationofriskfactorsforcolonizationwithmrs AT kunzelfrank prevalenceofmethicillinresistantstaphylococcusspmrsindifferentcompanionanimalsanddeterminationofriskfactorsforcolonizationwithmrs |