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Targeting Quorum Sensing: High-Throughput Screening to Identify Novel LsrK Inhibitors

Since quorum sensing (QS) is linked to the establishment of bacterial infection, its inactivation represents one of the newest strategies to fight bacterial pathogens. LsrK is a kinase playing a key role in the processing of autoinducer-2 (AI-2), a quorum-sensing mediator in gut enteric bacteria. In...

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Detalles Bibliográficos
Autores principales:	Gatta, Viviana, Ilina, Polina, Porter, Alison, McElroy, Stuart, Tammela, Päivi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627609/ https://www.ncbi.nlm.nih.gov/pubmed/31242708 http://dx.doi.org/10.3390/ijms20123112

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