Unusual Placement of an EBV Epitope into the Groove of the Ankylosing Spondylitis-Associated HLA-B27 Allele Allows CD8+ T Cell Activation

The human leukocyte antigen HLA-B27 is a strong risk factor for Ankylosing Spondylitis (AS), an immune-mediated disorder affecting axial skeleton and sacroiliac joints. Additionally, evidence exists sustaining a strong protective role for HLA-B27 in viral infections. These two aspects could stem fro...

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Detalles Bibliográficos
Autores principales: Tedeschi, Valentina, Alba, Josephine, Paladini, Fabiana, Paroli, Marino, Cauli, Alberto, Mathieu, Alessandro, Sorrentino, Rosa, D’Abramo, Marco, Fiorillo, Maria Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627668/
https://www.ncbi.nlm.nih.gov/pubmed/31212633
http://dx.doi.org/10.3390/cells8060572

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