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Loss of PTEN in Fallopian Tube Epithelium Results in Multicellular Tumor Spheroid Formation and Metastasis to the Ovary

High-grade serous ovarian cancer (HGSOC) can originate in the fallopian tube and then spread to the ovary. Our objective was to evaluate the role of multicellular tumor spheroids (MTS) in ovarian metastasis. By testing a panel of murine oviductal epithelial (MOE) cells with genetic alterations mimic...

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Detalles Bibliográficos
Autores principales:	Dean, Matthew, Jin, Vivian, Bergsten, Tova M., Austin, Julia R., Lantvit, Daniel D., Russo, Angela, Burdette, Joanna E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627669/ https://www.ncbi.nlm.nih.gov/pubmed/31242614 http://dx.doi.org/10.3390/cancers11060884

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