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NOS2 inhibitor 1400W Induces Autophagic Flux and Influences Extracellular Vesicle Profile in Human Glioblastoma U87MG Cell Line
The relevance of nitric oxide synthase 2 (NOS2) as a prognostic factor in Glioblastoma Multiforme (GBM) malignancy is emerging. We analyzed the effect of NOS2 inhibitor 1400W on the autophagic flux and extracellular vesicle (EV) secretion in U87MG glioma cells. The effects of glioma stem cells (GSC)...
Autores principales: | Palumbo, Paola, Lombardi, Francesca, Augello, Francesca Rosaria, Giusti, Ilaria, Luzzi, Sabino, Dolo, Vincenza, Cifone, Maria Grazia, Cinque, Benedetta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627770/ https://www.ncbi.nlm.nih.gov/pubmed/31226744 http://dx.doi.org/10.3390/ijms20123010 |
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