Cargando…

Transplantation of Adipose Stromal Cell Sheet Producing Hepatocyte Growth Factor Induces Pleiotropic Effect in Ischemic Skeletal Muscle

Cell therapy remains a promising approach for the treatment of cardiovascular diseases. In this regard, the contemporary trend is the development of methods to overcome low cell viability and enhance their regenerative potential. In the present study, we evaluated the therapeutic potential of gene-m...

Descripción completa

Detalles Bibliográficos
Autores principales:	Boldyreva, Maria A., Shevchenko, Evgeny K., Molokotina, Yuliya D., Makarevich, Pavel I., Beloglazova, Irina B., Zubkova, Ekaterina S., Dergilev, Konstantin V., Tsokolaeva, Zoya I., Penkov, Dmitry, Hsu, Mu-Nung, Hu, Yu-Chen, Parfyonova, Yelena V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627773/ https://www.ncbi.nlm.nih.gov/pubmed/31238604 http://dx.doi.org/10.3390/ijms20123088

Ejemplares similares

Cell Sheet Comprised of Mesenchymal Stromal Cells Overexpressing Stem Cell Factor Promotes Epicardium Activation and Heart Function Improvement in a Rat Model of Myocardium Infarction
por: Dergilev, Konstantin V., et al.
Publicado: (2020)

Angiogenic and pleiotropic effects of VEGF165 and HGF combined gene therapy in a rat model of myocardial infarction
por: Makarevich, Pavel I., et al.
Publicado: (2018)

C-Kit Cardiac Progenitor Cell Based Cell Sheet Improves Vascularization and Attenuates Cardiac Remodeling following Myocardial Infarction in Rats
por: Dergilev, K., et al.
Publicado: (2018)

Urokinase-Type Plasminogen Activator Receptor Regulates Prosurvival and Angiogenic Properties of Cardiac Mesenchymal Stromal Cells
por: Dergilev, Konstantin, et al.
Publicado: (2023)

New Insight on 2D In Vitro Angiogenesis Models: All That Stretches Is Not a Tube
por: Beloglazova, Irina, et al.
Publicado: (2022)

Combined Transfer of Human VEGF165 and HGF Genes Renders Potent Angiogenic Effect in Ischemic Skeletal Muscle
por: Makarevich, Pavel, et al.
Publicado: (2012)

Transplantation of modified human adipose derived stromal cells expressing VEGF165 results in more efficient angiogenic response in ischemic skeletal muscle
por: Shevchenko, Evgeny K, et al.
Publicado: (2013)

Transduction of rat and human adipose-tissue derived mesenchymal stromal cells by adeno-associated viral vector serotype DJ
por: Zubkova, Ekaterina S., et al.
Publicado: (2021)

Enhanced angiogenesis in ischemic skeletal muscle after transplantation of cell sheets from baculovirus-transduced adipose-derived stromal cells expressing VEGF165
por: Makarevich, Pavel I., et al.
Publicado: (2015)

Tn5 DNA Transposase in Multi-Omics Research
por: Penkov, Dmitry, et al.
Publicado: (2023)

Analysis of MicroRNA Profile Alterations in Extracellular Vesicles From Mesenchymal Stromal Cells Overexpressing Stem Cell Factor
por: Zubkova, Ekaterina, et al.
Publicado: (2021)

Autophagy, Mesenchymal Stem Cell Differentiation, and Secretion
por: Menshikov, Mikhail, et al.
Publicado: (2021)

Therapeutic Angiogenesis by a “Dynamic Duo”: Simultaneous Expression of HGF and VEGF165 by Novel Bicistronic Plasmid Restores Blood Flow in Ischemic Skeletal Muscle
por: Slobodkina, Ekaterina, et al.
Publicado: (2020)

CRISPR-based Activation of Endogenous Neurotrophic Genes in Adipose Stem Cell Sheets to Stimulate Peripheral Nerve Regeneration
por: Hsu, Mu-Nung, et al.
Publicado: (2019)

The Efficacy of HGF/VEGF Gene Therapy for Limb Ischemia in Mice with Impaired Glucose Tolerance: Shift from Angiogenesis to Axonal Growth and Oxidative Potential in Skeletal Muscle
por: Stafeev I, Iurii S., et al.
Publicado: (2022)

Oligonucleotide Microarrays Identified Potential Regulatory Genes Related to Early Outward Arterial Remodeling Induced by Tissue Plasminogen Activator
por: Plekhanova, Olga, et al.
Publicado: (2019)

Multifaced Roles of the Urokinase System in the Regulation of Stem Cell Niches
por: Dergilev, K. V., et al.
Publicado: (2018)

Grain-Based Dietary Background Impairs Restoration of Blood Flow and Skeletal Muscle During Hindlimb Ischemia in Comparison With Low-Fat and High-Fat Diets
por: Stafeev, Iurii, et al.
Publicado: (2022)

Calling and Phasing of Single-Nucleotide and Structural Variants of the LDLR Gene Using Oxford Nanopore MinION
por: Nazarenko, Maria S., et al.
Publicado: (2023)

A Novel Thromboplastin-Based Rat Model of Ischemic Stroke
por: Ostrova, Irina V., et al.
Publicado: (2021)

Transplantation of Adipose-Tissue-Engineered Constructs with CRISPR-Mediated UCP1 Activation
por: Michurina, Svetlana, et al.
Publicado: (2023)

Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases
por: He, Liang, et al.
Publicado: (2016)

In vitro ballooned hepatocytes can be produced by primary human hepatocytes and hepatic stellate cell sheets
por: Hasui, Nobuhiro, et al.
Publicado: (2022)

Corrigendum: Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases
por: He, Liang, et al.
Publicado: (2018)

Rapid production of engineered human primary hepatocyte/fibroblast sheets
por: Sakai, Yusuke, et al.
Publicado: (2015)

Hepatocyte Transplantation: Cell Sheet Technology for Liver Cell Transplantation
por: Tatsumi, Kohei, et al.
Publicado: (2017)

Endothelial and smooth muscle cells derived from human cardiac explants demonstrate angiogenic potential and suitable for design of cell-containing vascular grafts
por: Zakharova, I. S., et al.
Publicado: (2017)

Why does melanoma metastasize into the brain? Genes with pleiotropic effects might be the key
por: Yashin, Anatoliy I., et al.
Publicado: (2013)

Pleiotropic Associations of Allelic Variants in a 2q22 Region with Risks of Major Human Diseases and Mortality
por: Kulminski, Alexander M., et al.
Publicado: (2016)

Autologous Stem Cell Therapy: How Aging and Chronic Diseases Affect Stem and Progenitor Cells
por: Efimenko, Anastasia Yu., et al.
Publicado: (2015)

Self-Organization Provides Cell Fate Commitment in MSC Sheet Condensed Areas via ROCK-Dependent Mechanism
por: Nimiritsky, Peter, et al.
Publicado: (2021)

Generalized Harish-Chandra Modules
por: Penkov, I, et al.
Publicado: (2000)

Changes in the proteomic profile of blood serum in coronary atherosclerosis
por: Stakhneva, Ekaterina M., et al.
Publicado: (2020)

The pleiotropic effects of metformin: time for prospective studies
por: Bromage, Daniel I, et al.
Publicado: (2015)

Growth Factors in Regeneration and Regenerative Medicine: “the Cure and the Cause”
por: Kulebyakin, Konstantin Yu., et al.
Publicado: (2020)

A Proteomic Study of Atherosclerotic Plaques in Men with Coronary Atherosclerosis
por: Stakhneva, Ekaterina M., et al.
Publicado: (2019)

Self‐Organizing Human Induced Pluripotent Stem Cell Hepatocyte 3D Organoids Inform the Biology of the Pleiotropic TRIB1 Gene
por: Abbey, Deepti, et al.
Publicado: (2020)

Urokinase System in Pathogenesis of Pulmonary Fibrosis: A Hidden Threat of COVID-19
por: Shmakova, Anna A., et al.
Publicado: (2023)

Type 2 Diabetes Mellitus Facilitates Shift of Adipose-Derived Stem Cells Ex Vivo Differentiation toward Osteogenesis among Patients with Obesity
por: Agareva, Margarita, et al.
Publicado: (2022)

Pleiotropic effects of incretins
por: Gupta, Vishal
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_6bolidagl8g9dgemgnimpnk42c