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The cGMP Pathway and Inherited Photoreceptor Degeneration: Targets, Compounds, and Biomarkers

Photoreceptor physiology and pathophysiology is intricately linked to guanosine-3’,5’-cyclic monophosphate (cGMP)-signaling. Here, we discuss the importance of cGMP-signaling for the pathogenesis of hereditary retinal degeneration. Excessive accumulation of cGMP in photoreceptors is a common denomin...

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Detalles Bibliográficos
Autores principales:	Tolone, Arianna, Belhadj, Soumaya, Rentsch, Andreas, Schwede, Frank, Paquet-Durand, François
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627777/ https://www.ncbi.nlm.nih.gov/pubmed/31207907 http://dx.doi.org/10.3390/genes10060453

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