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Validation of Immunohistochemistry for the Detection of BRAF V600E-Mutated Lung Adenocarcinomas
BRAF V600E mutation, a missense mutation in exon 15 resulting in valine substitution for glutamate at position 600 within the kinase domain of BRAF oncogene, is found in a subset of lung adenocarcinoma (ADC). The usefulness of immunohistochemistry (IHC) as an alternative diagnostic tool has not been...
Autores principales: | Gow, Chien-Hung, Hsieh, Min-Shu, Lin, Yen-Ting, Liu, Yi-Nan, Shih, Jin-Yuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627826/ https://www.ncbi.nlm.nih.gov/pubmed/31234388 http://dx.doi.org/10.3390/cancers11060866 |
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