Cargando…

Collagen 1A1 (COL1A1) Is a Reliable Biomarker and Putative Therapeutic Target for Hepatocellular Carcinogenesis and Metastasis

Increasing evidence shows that hepatocellular carcinoma (HCC) is a principal cause of cancer-related mortality globally, especially among Asian and African populations. Collagen type I α1 (COL1A1) is the major component of type I collagen. While aberrant expression of COL1A1 and COL1A2 is implicated...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ma, Hon-Ping, Chang, Hang-Lung, Bamodu, Oluwaseun Adebayo, Yadav, Vijesh Kumar, Huang, Ting-Yi, Wu, Alexander T. H., Yeh, Chi-Tai, Tsai, Shin-Han, Lee, Wei-Hwa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627889/ https://www.ncbi.nlm.nih.gov/pubmed/31181620 http://dx.doi.org/10.3390/cancers11060786

Ejemplares similares

Targeting the Epigenetic Non-Coding RNA MALAT1/Wnt Signaling Axis as a Therapeutic Approach to Suppress Stemness and Metastasis in Hepatocellular Carcinoma
por: Chang, Hang-Lung, et al.
Publicado: (2020)

Elevated PDK1 Expression Drives PI3K/AKT/MTOR Signaling Promotes Radiation-Resistant and Dedifferentiated Phenotype of Hepatocellular Carcinoma
por: Bamodu, Oluwaseun Adebayo, et al.
Publicado: (2020)

SUMO-Activating Enzyme Subunit 1 (SAE1) Is a Promising Diagnostic Cancer Metabolism Biomarker of Hepatocellular Carcinoma
por: Ong, Jiann Ruey, et al.
Publicado: (2021)

Targeting FAT1 Inhibits Carcinogenesis, Induces Oxidative Stress and Enhances Cisplatin Sensitivity through Deregulation of LRP5/WNT2/GSS Signaling Axis in Oral Squamous Cell Carcinoma
por: Hsu, Tung-Nien, et al.
Publicado: (2019)

Targeted PARP Inhibition Combined with FGFR1 Blockade is Synthetically Lethal to Malignant Cells in Patients with Pancreatic Cancer
por: Lai, Shiue-Wei, et al.
Publicado: (2020)

Histone demethylase JARID1B/KDM5B promotes aggressiveness of non-small cell lung cancer and serves as a good prognostic predictor
por: Kuo, Kuang-Tai, et al.
Publicado: (2018)

Aberrant KDM5B expression promotes aggressive breast cancer through MALAT1 overexpression and downregulation of hsa-miR-448
por: Bamodu, Oluwaseun Adebayo, et al.
Publicado: (2016)

Exosomal lncRNA PVT1/VEGFA Axis Promotes Colon Cancer Metastasis and Stemness by Downregulation of Tumor Suppressor miR-152-3p
por: Lai, Shiue-Wei, et al.
Publicado: (2021)

Collagen COL22A1 maintains vascular stability and mutations in COL22A1 are potentially associated with intracranial aneurysms
por: Ton, Quynh V., et al.
Publicado: (2018)

A cross-country comparison of malaria policy as a premise for contextualized appropriation of foreign aid in global health
por: Jezek, Tomas, et al.
Publicado: (2021)

Mutant collagen COL11A1 enhances cancerous invasion
por: Lee, Carolyn S., et al.
Publicado: (2021)

Artificial neural network based prediction of postthrombolysis intracerebral hemorrhage and death
por: Chung, Chen-Chih, et al.
Publicado: (2020)

Neurofilament light chain level in plasma extracellular vesicles and Parkinson’s disease
por: Chung, Chen-Chih, et al.
Publicado: (2020)

Blood Neurofilament Light Chain in Parkinson’s Disease: Comparability between Parkinson’s Progression Markers Initiative (PPMI) and Asian Cohorts
por: Chen, Jia-Hung, et al.
Publicado: (2021)

Astragalus polysaccharides (PG2) Enhances the M1 Polarization of Macrophages, Functional Maturation of Dendritic Cells, and T Cell-Mediated Anticancer Immune Responses in Patients with Lung Cancer
por: Bamodu, Oluwaseun Adebayo, et al.
Publicado: (2019)

JARID1B Expression Plays a Critical Role in Chemoresistance and Stem Cell-Like Phenotype of Neuroblastoma Cells
por: Kuo, Yung-Ting, et al.
Publicado: (2015)

Collagen fiber features and COL1A1: are they associated with elastic parameters in breast lesions, and can COL1A1 predict axillary lymph node metastasis?
por: Jiang, Ying, et al.
Publicado: (2022)

Experimental murine myopia induces collagen type Iα1 (COL1A1) DNA methylation and altered COL1A1 messenger RNA expression in sclera
por: Zhou, Xiangtian, et al.
Publicado: (2012)

Radiation increases COL1A1, COL3A1, and COL1A2 expression in breast cancer
por: Yao, Guorong, et al.
Publicado: (2022)

Collagen type IV alpha 1 (COL4A1) and collagen type XIII alpha 1 (COL13A1) produced in cancer cells promote tumor budding at the invasion front in human urothelial carcinoma of the bladder
por: Miyake, Makito, et al.
Publicado: (2017)

Differential Expression of COL1A1, COL1A2, COL6A3, and SULF1 as Prognostic Biomarkers in Gastric Cancer
por: Hu, Yan, et al.
Publicado: (2021)

Artificial neural network-boosted Cardiac Arrest Survival Post-Resuscitation In-hospital (CASPRI) score accurately predicts outcome in cardiac arrest patients treated with targeted temperature management
por: Chou, Szu-Yi, et al.
Publicado: (2022)

Dysregulated expression of slingshot protein phosphatase 1 (SSH1) disrupts circadian rhythm and WNT signaling associated to hepatocellular carcinoma pathogenesis
por: Lai, Shiue-Wei, et al.
Publicado: (2023)

Ovatodiolide Suppresses Oral Cancer Malignancy by Down-Regulating Exosomal Mir-21/STAT3/β-Catenin Cargo and Preventing Oncogenic Transformation of Normal Gingival Fibroblasts
por: Chen, Jia-Hong, et al.
Publicado: (2019)

The Disruption of the β-Catenin/TCF-1/STAT3 Signaling Axis by 4-Acetylantroquinonol B Inhibits the Tumorigenesis and Cancer Stem-Cell-Like Properties of Glioblastoma Cells, In Vitro and In Vivo
por: Liu, Heng-Wei, et al.
Publicado: (2018)

Collagen IV (COL4A1, COL4A2), a Component of the Viral Biofilm, Is Induced by the HTLV-1 Oncoprotein Tax and Impacts Virus Transmission
por: Millen, Sebastian, et al.
Publicado: (2019)

Furanocoumarin Notopterol: Inhibition of Hepatocellular Carcinogenesis through Suppression of Cancer Stemness Signaling and Induction of Oxidative Stress-Associated Cell Death
por: Huang, Ting-Yun, et al.
Publicado: (2023)

Identification of COL1A1 and COL1A2 as candidate prognostic factors in gastric cancer
por: Li, Jun, et al.
Publicado: (2016)

The impact of COL1A1 and COL6A1 expression on hypospadias and penile curvature severity
por: Yuri, Prahara, et al.
Publicado: (2020)

Reviewing the Regulators of COL1A1
por: Devos, Hanne, et al.
Publicado: (2023)

Collagen Type I alpha1 (COL1A1) Gene Polymorphism and Bone Mineral Density in Postmenopausal Kazakh Women
por: Aitkulova, Akbota, et al.
Publicado: (2014)

Identification of the collagen type 1 alpha 1 gene (COL1A1) as a candidate survival-related factor associated with hepatocellular carcinoma
por: Hayashi, Masamichi, et al.
Publicado: (2014)

Osteoblasts mineralization and collagen matrix are conserved upon specific Col1a2 silencing
por: Maruelli, Silvia, et al.
Publicado: (2020)

Post-valvular surgery multi-vessel coronary artery spasm — A literature review
por: Formica, Francesco, et al.
Publicado: (2015)

Collagen Type XI Alpha 1 (COL11A1): A Novel Biomarker and a Key Player in Cancer
por: Nallanthighal, Sameera, et al.
Publicado: (2021)

Authentication of a novel antibody to zebrafish collagen type XI alpha 1 chain (Col11a1a)
por: Reeck, Jonathon C., et al.
Publicado: (2021)

Combined Treatment with Acalabrutinib and Rapamycin Inhibits Glioma Stem Cells and Promotes Vascular Normalization by Downregulating BTK/mTOR/VEGF Signaling
por: Su, Yu-Kai, et al.
Publicado: (2021)

MED10 Drives the Oncogenicity and Refractory Phenotype of Bladder Urothelial Carcinoma Through the Upregulation of hsa-miR-590
por: Wu, Chia-Chang, et al.
Publicado: (2022)

Mutation analysis of the COL1A1 and COL1A2 genes in Vietnamese patients with osteogenesis imperfecta
por: Ho Duy, Binh, et al.
Publicado: (2016)

Rare functional genetic variants in COL7A1, COL6A5, COL1A2 and COL5A2 frequently occur in Chiari Malformation Type 1
por: Urbizu, Aintzane, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_f9a0dsks2ggln2dm2h01vjp3hl