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Luminescence- and Fluorescence-Based Complementation Assays to Screen for GPCR Oligomerization: Current State of the Art

G protein-coupled receptors (GPCRs) have the propensity to form homo- and heterodimers. Dysfunction of these dimers has been associated with multiple diseases, e.g., pre-eclampsia, schizophrenia, and depression, among others. Over the past two decades, considerable efforts have been made towards the...

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Detalles Bibliográficos
Autores principales: Wouters, Elise, Vasudevan, Lakshmi, Crans, René A. J., Saini, Deepak K., Stove, Christophe P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627893/
https://www.ncbi.nlm.nih.gov/pubmed/31213021
http://dx.doi.org/10.3390/ijms20122958