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Luminescence- and Fluorescence-Based Complementation Assays to Screen for GPCR Oligomerization: Current State of the Art
G protein-coupled receptors (GPCRs) have the propensity to form homo- and heterodimers. Dysfunction of these dimers has been associated with multiple diseases, e.g., pre-eclampsia, schizophrenia, and depression, among others. Over the past two decades, considerable efforts have been made towards the...
Autores principales: | Wouters, Elise, Vasudevan, Lakshmi, Crans, René A. J., Saini, Deepak K., Stove, Christophe P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627893/ https://www.ncbi.nlm.nih.gov/pubmed/31213021 http://dx.doi.org/10.3390/ijms20122958 |
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