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Mitochondrial Transport and Turnover in the Pathogenesis of Amyotrophic Lateral Sclerosis
Neurons are high-energy consuming cells, heavily dependent on mitochondria for ATP generation and calcium buffering. These mitochondrial functions are particularly critical at specific cellular sites, where ionic currents impose a large energetic burden, such as at synapses. The highly polarized nat...
Autores principales: | Granatiero, Veronica, Manfredi, Giovanni |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627920/ https://www.ncbi.nlm.nih.gov/pubmed/31083575 http://dx.doi.org/10.3390/biology8020036 |
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