Cargando…

Thrombin Preconditioning Boosts Biogenesis of Extracellular Vesicles from Mesenchymal Stem Cells and Enriches Their Cargo Contents via Protease-Activated Receptor-Mediated Signaling Pathways

We investigated the role of protease-activated receptor (PAR)-mediated signaling pathways in the biogenesis of human umbilical cord blood-derived mesenchymal stem cell (MSC)-derived extracellular vesicles (EVs) and the enrichment of their cargo content after thrombin preconditioning. Immunoblot anal...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sung, Dong Kyung, Sung, Se In, Ahn, So Yoon, Chang, Yun Sil, Park, Won Soon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627943/ https://www.ncbi.nlm.nih.gov/pubmed/31197089 http://dx.doi.org/10.3390/ijms20122899

Ejemplares similares

Thrombin Preconditioning of Extracellular Vesicles Derived from Mesenchymal Stem Cells Accelerates Cutaneous Wound Healing by Boosting Their Biogenesis and Enriching Cargo Content
por: Sung, Dong Kyung, et al.
Publicado: (2019)

Thrombin Preconditioning Enhances Therapeutic Efficacy of Human Wharton’s Jelly–Derived Mesenchymal Stem Cells in Severe Neonatal Hypoxic Ischemic Encephalopathy
por: Kim, Young Eun, et al.
Publicado: (2019)

Thrombin Preconditioning Improves the Therapeutic Efficacy of Mesenchymal Stem Cells in Severe Intraventricular Hemorrhage Induced Neonatal Rats
por: Jung, So Yeon, et al.
Publicado: (2022)

Neuroinflammatory Modulation of Extracellular Vesicle Biogenesis and Cargo Loading
por: Spiers, Jereme G., et al.
Publicado: (2022)

Extracellular Vesicles Biogenesis, Cargo Sorting and Implications in Disease Conditions
por: Fonseka, Pamali, et al.
Publicado: (2023)

Role of Ceramides and Lysosomes in Extracellular Vesicle Biogenesis, Cargo Sorting and Release
por: Horbay, Rostyslav, et al.
Publicado: (2022)

Extracellular vesicles in β cell biology: Role of lipids in vesicle biogenesis, cargo, and intercellular signaling
por: Aguirre, Rebecca S., et al.
Publicado: (2022)

Evaluation of the cargo contents and potential role of extracellular vesicles in osteoporosis
por: Xu, Jifeng, et al.
Publicado: (2021)

Menstrual blood-derived mesenchymal stromal cells: impact of preconditioning on the cargo of extracellular vesicles as potential therapeutics
por: de Pedro, María Ángeles, et al.
Publicado: (2023)

The Extracellular Vesicles of the Helminth Pathogen, Fasciola hepatica: Biogenesis Pathways and Cargo Molecules Involved in Parasite Pathogenesis
por: Cwiklinski, Krystyna, et al.
Publicado: (2015)

Presynaptic Precursor Vesicles—Cargo, Biogenesis, and Kinesin-Based Transport across Species
por: Petzoldt, Astrid G.
Publicado: (2023)

Neurons Export Extracellular Vesicles Enriched in Cysteine String Protein and Misfolded Protein Cargo
por: Deng, Jingti, et al.
Publicado: (2017)

Variability in protein cargo detection in technical and biological replicates of exosome-enriched extracellular vesicles
por: Tiruvayipati, Suma, et al.
Publicado: (2020)

Hypoxic Preconditioned Neural Stem Cell-Derived Extracellular Vesicles Contain Distinct Protein Cargo from Their Normal Counterparts
por: Gharbi, Tahereh, et al.
Publicado: (2023)

Mesenchymal-Stem-Cell-Derived Extracellular Vesicles Attenuate Brain Injury in Escherichia coli Meningitis in Newborn Rats
por: Kim, Young-Eun, et al.
Publicado: (2022)

Preclinical assessment of thrombin‐preconditioned human Wharton’s jelly‐derived mesenchymal stem cells for neonatal hypoxic‐ischaemic brain injury
por: Noh, Jung‐Ho, et al.
Publicado: (2021)

Vascular endothelial growth factor mediates the therapeutic efficacy of mesenchymal stem cell-derived extracellular vesicles against neonatal hyperoxic lung injury
por: Ahn, So Yoon, et al.
Publicado: (2018)

Mitochondria as extracellular vesicle cargo in aging
por: Noren Hooten, Nicole, et al.
Publicado: (2021)

Mechanism of cargo sorting into small extracellular vesicles
por: Chen, Yiwen, et al.
Publicado: (2021)

Circadian regulation of protein cargo in extracellular vesicles
por: Yeung, Ching-Yan Chloé, et al.
Publicado: (2022)

Targeting nucleic acid sensors in tumor cells to reprogram biogenesis and RNA cargo of extracellular vesicles for T cell-mediated cancer immunotherapy
por: Heidegger, Simon, et al.
Publicado: (2023)

Reconstitution of Mitochondria Derived Vesicle Formation Demonstrates Selective Enrichment of Oxidized Cargo
por: Soubannier, Vincent, et al.
Publicado: (2012)

Brain‐derived neurotropic factor mediates neuroprotection of mesenchymal stem cell‐derived extracellular vesicles against severe intraventricular hemorrhage in newborn rats
por: Ahn, So Yoon, et al.
Publicado: (2020)

Platelet-released extracellular vesicles: the effects of thrombin activation
por: Suades, Rosa, et al.
Publicado: (2022)

Extracellular Vesicles as Delivery Vehicles of Specific Cellular Cargo
por: Mir, Bilal, et al.
Publicado: (2020)

Endocytosis of Extracellular Vesicles and Release of Their Cargo from Endosomes
por: Joshi, Bhagyashree S., et al.
Publicado: (2020)

Coordination of fungal biofilm development by extracellular vesicle cargo
por: Zarnowski, Robert, et al.
Publicado: (2021)

The Complicated Effects of Extracellular Vesicles and Their Cargos on Embryo Implantation
por: Jiang, Nan-Xing, et al.
Publicado: (2021)

The role of the metabolite cargo of extracellular vesicles in tumor progression
por: Harmati, Mária, et al.
Publicado: (2021)

Overview and Update on Methods for Cargo Loading into Extracellular Vesicles
por: Han, Yohan, et al.
Publicado: (2021)

Extracellular Vesicles Cargo in Modulating Microglia Functional Responses
por: La Torre, Maria Ester, et al.
Publicado: (2022)

Ageing-associated small RNA cargo of extracellular vesicles
por: Kern, Fabian, et al.
Publicado: (2023)

Mesenchymal Stromal Cells Primed by Toll-like Receptors 3 and 4 Enhanced Anti-Inflammatory Effects against LPS-Induced Macrophages via Extracellular Vesicles
por: Hwang, Sein, et al.
Publicado: (2023)

Extracellular signals regulate the biogenesis of extracellular vesicles
por: Jin, Yong, et al.
Publicado: (2022)

The Role of Extracellular Vesicles in Cancer: Cargo, Function, and Therapeutic Implications
por: Jabalee, James, et al.
Publicado: (2018)

Biological surface properties in extracellular vesicles and their effect on cargo proteins
por: Santucci, Laura, et al.
Publicado: (2019)

Uptake, functionality, and re-release of extracellular vesicle-encapsulated cargo
por: O’Brien, Killian, et al.
Publicado: (2022)

Caspofungin Affects Extracellular Vesicle Production and Cargo in Candida auris
por: Amatuzzi, Rafaela F., et al.
Publicado: (2022)

Boosting extracellular vesicle secretion
por: Debbi, Lior, et al.
Publicado: (2022)

CLN8 is an ER cargo receptor that regulates lysosome biogenesis
por: di Ronza, Alberto, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_io2q65aj5rhbo6cr7sktak0pn8