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Class I-Histone Deacetylase (HDAC) Inhibition is Superior to pan-HDAC Inhibition in Modulating Cisplatin Potency in High Grade Serous Ovarian Cancer Cell Lines

High grade serous ovarian cancer (HGSOC) is the most common and aggressive ovarian cancer subtype with the worst clinical outcome due to intrinsic or acquired drug resistance. Standard treatment involves platinum compounds. Cancer development and chemoresistance is often associated with an increase...

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Detalles Bibliográficos
Autores principales: Bandolik, Jan J., Hamacher, Alexandra, Schrenk, Christian, Weishaupt, Robin, Kassack, Matthias U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627993/
https://www.ncbi.nlm.nih.gov/pubmed/31234549
http://dx.doi.org/10.3390/ijms20123052

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