Cellular Effects of Butyrate on Vascular Smooth Muscle Cells are Mediated through Disparate Actions on Dual Targets, Histone Deacetylase (HDAC) Activity and PI3K/Akt Signaling Network

Vascular remodeling is a characteristic feature of cardiovascular diseases. Altered cellular processes of vascular smooth muscle cells (VSMCs) is a crucial component in vascular remodeling. Histone deacetylase inhibitor (HDACI), butyrate, arrests VSMC proliferation and promotes cell growth. The obje...

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Detalles Bibliográficos
Autores principales: Mathew, Omana P., Ranganna, Kasturi, Mathew, Joseph, Zhu, Meiling, Yousefipour, Zivar, Selvam, Chelliah, Milton, Shirlette G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628026/
https://www.ncbi.nlm.nih.gov/pubmed/31197106
http://dx.doi.org/10.3390/ijms20122902

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628026/
https://www.ncbi.nlm.nih.gov/pubmed/31197106
http://dx.doi.org/10.3390/ijms20122902

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