Cargando…

Synthesis of “Dahlia-Like” Hydrophilic Fluorescent Carbon Nanohorn as a Bio-Imaging PROBE

Carbon nanohorns (CNH) were synthesized by a simple conventional hydrothermal method in this study. The CNHs were prepared by the chemical oxidation from the carbonation of Nafion (catalyst) with heparin (carbon resource). The formation of CNH involved two major steps, as described followed. First,...

Descripción completa

Detalles Bibliográficos
Autores principales: Parasuraman, Perumalswamy Sekar, Parasuraman, Vijaya Rohini, Anbazhagan, Rajeshkumar, Tsai, Hsieh-Chih, Lai, Juin-Yih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628057/
https://www.ncbi.nlm.nih.gov/pubmed/31216698
http://dx.doi.org/10.3390/ijms20122977
_version_ 1783434877264199680
author Parasuraman, Perumalswamy Sekar
Parasuraman, Vijaya Rohini
Anbazhagan, Rajeshkumar
Tsai, Hsieh-Chih
Lai, Juin-Yih
author_facet Parasuraman, Perumalswamy Sekar
Parasuraman, Vijaya Rohini
Anbazhagan, Rajeshkumar
Tsai, Hsieh-Chih
Lai, Juin-Yih
author_sort Parasuraman, Perumalswamy Sekar
collection PubMed
description Carbon nanohorns (CNH) were synthesized by a simple conventional hydrothermal method in this study. The CNHs were prepared by the chemical oxidation from the carbonation of Nafion (catalyst) with heparin (carbon resource). The formation of CNH involved two major steps, as described followed. First, the formation of carbon nanorice (CNR) was achieved by carbonation and self-assembly of heparin inside the Nafion structure. Second, the further oxidation of CNR resulted the heterogeneous and porous micelle domains showed at the outer layer of the CNR particles. These porous domains exhibited hydrophobic carbon and resulted self-assembly of the CNR to form the structure of CNHs. The resulting CNHs aggregated into a “dahlia-like” morphology with fluorescence in a diameter of 50–200 nm. The “dahlia-like” CNH showed better fluorescence (450nm) than CNR particles because of the presence of more structural defect. These findings suggest that the hydrophilic fluorescent carbon nanohorns (HFCNHs) synthesized in this study have the potential to be used for in vitro bio-imaging
format Online
Article
Text
id pubmed-6628057
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-66280572019-07-23 Synthesis of “Dahlia-Like” Hydrophilic Fluorescent Carbon Nanohorn as a Bio-Imaging PROBE Parasuraman, Perumalswamy Sekar Parasuraman, Vijaya Rohini Anbazhagan, Rajeshkumar Tsai, Hsieh-Chih Lai, Juin-Yih Int J Mol Sci Communication Carbon nanohorns (CNH) were synthesized by a simple conventional hydrothermal method in this study. The CNHs were prepared by the chemical oxidation from the carbonation of Nafion (catalyst) with heparin (carbon resource). The formation of CNH involved two major steps, as described followed. First, the formation of carbon nanorice (CNR) was achieved by carbonation and self-assembly of heparin inside the Nafion structure. Second, the further oxidation of CNR resulted the heterogeneous and porous micelle domains showed at the outer layer of the CNR particles. These porous domains exhibited hydrophobic carbon and resulted self-assembly of the CNR to form the structure of CNHs. The resulting CNHs aggregated into a “dahlia-like” morphology with fluorescence in a diameter of 50–200 nm. The “dahlia-like” CNH showed better fluorescence (450nm) than CNR particles because of the presence of more structural defect. These findings suggest that the hydrophilic fluorescent carbon nanohorns (HFCNHs) synthesized in this study have the potential to be used for in vitro bio-imaging MDPI 2019-06-18 /pmc/articles/PMC6628057/ /pubmed/31216698 http://dx.doi.org/10.3390/ijms20122977 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Parasuraman, Perumalswamy Sekar
Parasuraman, Vijaya Rohini
Anbazhagan, Rajeshkumar
Tsai, Hsieh-Chih
Lai, Juin-Yih
Synthesis of “Dahlia-Like” Hydrophilic Fluorescent Carbon Nanohorn as a Bio-Imaging PROBE
title Synthesis of “Dahlia-Like” Hydrophilic Fluorescent Carbon Nanohorn as a Bio-Imaging PROBE
title_full Synthesis of “Dahlia-Like” Hydrophilic Fluorescent Carbon Nanohorn as a Bio-Imaging PROBE
title_fullStr Synthesis of “Dahlia-Like” Hydrophilic Fluorescent Carbon Nanohorn as a Bio-Imaging PROBE
title_full_unstemmed Synthesis of “Dahlia-Like” Hydrophilic Fluorescent Carbon Nanohorn as a Bio-Imaging PROBE
title_short Synthesis of “Dahlia-Like” Hydrophilic Fluorescent Carbon Nanohorn as a Bio-Imaging PROBE
title_sort synthesis of “dahlia-like” hydrophilic fluorescent carbon nanohorn as a bio-imaging probe
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628057/
https://www.ncbi.nlm.nih.gov/pubmed/31216698
http://dx.doi.org/10.3390/ijms20122977
work_keys_str_mv AT parasuramanperumalswamysekar synthesisofdahlialikehydrophilicfluorescentcarbonnanohornasabioimagingprobe
AT parasuramanvijayarohini synthesisofdahlialikehydrophilicfluorescentcarbonnanohornasabioimagingprobe
AT anbazhaganrajeshkumar synthesisofdahlialikehydrophilicfluorescentcarbonnanohornasabioimagingprobe
AT tsaihsiehchih synthesisofdahlialikehydrophilicfluorescentcarbonnanohornasabioimagingprobe
AT laijuinyih synthesisofdahlialikehydrophilicfluorescentcarbonnanohornasabioimagingprobe