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Identification of Novel Anti-Liver Cancer Small Molecules with Better Therapeutic Index Than Sorafenib via Zebrafish Drug Screening Platform

Hepatocellular carcinoma (HCC) ranks as the fourth leading cause of cancer-related deaths worldwide. Sorafenib was the only U.S. Food and Drug Administration (FDA) approved drug for treating advanced HCC until recently, so development of new target therapy is urgently needed. In this study, we estab...

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Detalles Bibliográficos
Autores principales: Lin, Han-Syuan, Huang, Yi-Luen, Wang, Yi-Rui Stefanie, Hsiao, Eugene, Hsu, Tsu-An, Shiao, Hui-Yi, Jiaang, Weir-Torn, Sampurna, Bonifasius Putera, Lin, Kuan-Hao, Wu, Ming-Shun, Lai, Gi-Ming, Yuh, Chiou-Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628114/
https://www.ncbi.nlm.nih.gov/pubmed/31141996
http://dx.doi.org/10.3390/cancers11060739