Activation of Slit2/Robo1 Signaling Promotes Tumor Metastasis in Colorectal Carcinoma through Activation of the TGF-β/Smads Pathway

Slit2 (slit guidance ligand 2), a ligand of the Roundabout1 (Robo1) transmembrane receptor, is often overexpressed in colorectal carcinomas (CRCs). In this study, we performed data mining in the Metabolic gEne RApid Visualizer (MERAV) database and found that Slit2 and TGF-β1 (Transforming growth fac...

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Detalles Bibliográficos
Autores principales: Yao, Yuying, Zhou, Zijun, Li, Liuyou, Li, Junchen, Huang, Lixun, Li, Jiangchao, Qi, Cuiling, Zheng, Lingyun, Wang, Lijing, Zhang, Qian-Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628122/
https://www.ncbi.nlm.nih.gov/pubmed/31242633
http://dx.doi.org/10.3390/cells8060635

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