CD28 Autonomous Signaling Up-Regulates C-Myc Expression and Promotes Glycolysis Enabling Inflammatory T Cell Responses in Multiple Sclerosis

The immunopathogenesis of multiple sclerosis (MS) depend on the expansion of specific inflammatory T cell subsets, which are key effectors of tissue damage and demyelination. Emerging studies evidence that a reprogramming of T cell metabolism may occur in MS, thus the identification of stimulatory m...

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Detalles Bibliográficos
Autores principales: Kunkl, Martina, Sambucci, Manolo, Ruggieri, Serena, Amormino, Carola, Tortorella, Carla, Gasperini, Claudio, Battistini, Luca, Tuosto, Loretta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628233/
https://www.ncbi.nlm.nih.gov/pubmed/31212712
http://dx.doi.org/10.3390/cells8060575

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628233/
https://www.ncbi.nlm.nih.gov/pubmed/31212712
http://dx.doi.org/10.3390/cells8060575

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