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Suppression of STAT3 Phosphorylation and RelA/p65 Acetylation Mediated by MicroRNA134 Plays a Pivotal Role in the Apoptotic Effect of Lambertianic Acid

As p300-mediated RelA/p65 hyperacetylation by signal transducers and activators of transcription 3 (STAT3) is critical for NF-κB activation, in the current study, the apoptotic mechanism of lambertianic acid (LA) was explored in relation to STAT3 phosphorylation and RelA/p65 acetylation in MCF-7, DU...

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Detalles Bibliográficos
Autores principales: Sim, Deok Yong, Lee, Hyo-Jung, Jung, Ji Hoon, Im, Eunji, Hwang, Jisung, Kim, Dong Sub, Kim, Sung-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628272/
https://www.ncbi.nlm.nih.gov/pubmed/31248140
http://dx.doi.org/10.3390/ijms20122993