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Activation of TrkB/Akt signaling by a TrkB receptor agonist improves long-term histological and functional outcomes in experimental intracerebral hemorrhage

BACKGROUND: Intracerebral hemorrhage (ICH) induces a complex sequence of apoptotic cascades that contribute to secondary neuronal damage. Tropomyosin-related kinase receptor B (TrkB) signaling plays a crucial role in promoting neuronal survival following brain damage. METHODS: The present study inve...

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Detalles Bibliográficos
Autores principales: Wu, Chun-Hu, Chen, Chien-Cheng, Hung, Tai-Ho, Chuang, Yen-Chieh, Chao, Min, Shyue, Song-Kun, Chen, Szu-Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628494/
https://www.ncbi.nlm.nih.gov/pubmed/31307481
http://dx.doi.org/10.1186/s12929-019-0543-8

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