Relationship between Multiple Sclerosis-Associated IL2RA Risk Allele Variants and Circulating T Cell Phenotypes in Healthy Genotype-Selected Controls

Single nucleotide polymorphisms (SNPs) in or near the IL2RA gene, that encodes the interleukin-2 (IL-2) receptor α (CD25), are associated with increased risk of immune-mediated diseases including multiple sclerosis (MS). We investigated how the MS-associated IL2RA SNPs rs2104286 and rs11256593 are a...

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Detalles Bibliográficos
Autores principales: Buhelt, Sophie, Søndergaard, Helle Bach, Oturai, Annette, Ullum, Henrik, von Essen, Marina Rode, Sellebjerg, Finn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628508/
https://www.ncbi.nlm.nih.gov/pubmed/31242590
http://dx.doi.org/10.3390/cells8060634

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628508/
https://www.ncbi.nlm.nih.gov/pubmed/31242590
http://dx.doi.org/10.3390/cells8060634

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