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Relationship between Multiple Sclerosis-Associated IL2RA Risk Allele Variants and Circulating T Cell Phenotypes in Healthy Genotype-Selected Controls
Single nucleotide polymorphisms (SNPs) in or near the IL2RA gene, that encodes the interleukin-2 (IL-2) receptor α (CD25), are associated with increased risk of immune-mediated diseases including multiple sclerosis (MS). We investigated how the MS-associated IL2RA SNPs rs2104286 and rs11256593 are a...
Autores principales: | Buhelt, Sophie, Søndergaard, Helle Bach, Oturai, Annette, Ullum, Henrik, von Essen, Marina Rode, Sellebjerg, Finn |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628508/ https://www.ncbi.nlm.nih.gov/pubmed/31242590 http://dx.doi.org/10.3390/cells8060634 |
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