Characterization of acquired receptor tyrosine–kinase fusions as mechanisms of resistance to EGFR tyrosine–kinase inhibitors

Purpose: Responses to EGFR-targeted therapy are generally temporary, due to inevitable drug resistance. The prevalence and characteristics of receptor tyrosine–kinase (RTK) fusion as acquired resistance to EGFR tyrosine–kinase inhibitors (TKIs) are rarely investigated. Methods: We retrospectively re...

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Detalles Bibliográficos
Autores principales: Xu, Haiyuan, Shen, Jinge, Xiang, Jianxing, Li, Haiyan, Li, Bing, Zhang, Tengfei, Zhang, Lu, Mao, Xinru, Jian, Hong, Shu, Yongqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628603/
https://www.ncbi.nlm.nih.gov/pubmed/31372039
http://dx.doi.org/10.2147/CMAR.S197337

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628603/
https://www.ncbi.nlm.nih.gov/pubmed/31372039
http://dx.doi.org/10.2147/CMAR.S197337

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