Enabling microbial syringol conversion through structure-guided protein engineering

Microbial conversion of aromatic compounds is an emerging and promising strategy for valorization of the plant biopolymer lignin. A critical and often rate-limiting reaction in aromatic catabolism is O-aryl-demethylation of the abundant aromatic methoxy groups in lignin to form diols, which enables...

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Detalles Bibliográficos
Autores principales: Machovina, Melodie M., Mallinson, Sam J. B., Knott, Brandon C., Meyers, Alexander W., Garcia-Borràs, Marc, Bu, Lintao, Gado, Japheth E., Oliver, April, Schmidt, Graham P., Hinchen, Daniel J., Crowley, Michael F., Johnson, Christopher W., Neidle, Ellen L., Payne, Christina M., Houk, Kendall N., Beckham, Gregg T., McGeehan, John E., DuBois, Jennifer L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628648/
https://www.ncbi.nlm.nih.gov/pubmed/31235604
http://dx.doi.org/10.1073/pnas.1820001116

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