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Structure-guided examination of the mechanogating mechanism of PIEZO2

Piezo channels are mechanically activated ion channels that confer mechanosensitivity to a variety of different cell types. Piezos oligomerize as propeller-shaped homotrimers that are thought to locally curve the membrane into spherical domes that project into the cell. While several studies have id...

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Detalles Bibliográficos
Autores principales: Taberner, Francisco J., Prato, Vincenzo, Schaefer, Irina, Schrenk-Siemens, Katrin, Heppenstall, Paul A., Lechner, Stefan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628815/
https://www.ncbi.nlm.nih.gov/pubmed/31235572
http://dx.doi.org/10.1073/pnas.1905985116

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