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Robust single-cell Hi-C clustering by convolution- and random-walk–based imputation
Three-dimensional genome structure plays a pivotal role in gene regulation and cellular function. Single-cell analysis of genome architecture has been achieved using imaging and chromatin conformation capture methods such as Hi-C. To study variation in chromosome structure between different cell typ...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628819/ https://www.ncbi.nlm.nih.gov/pubmed/31235599 http://dx.doi.org/10.1073/pnas.1901423116 |