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TGF-β1 enhances FOXO3 expression in human synovial fibroblasts by inhibiting miR-92a through AMPK and p38 pathways
Osteoarthritis (OA) is an age-related disease marked by synovial inflammation and cartilage destruction arising from synovitis, joint swelling and pain. OA therapy that targets the synovium is a promising strategy for mitigating the symptoms and disease progression. Altered activity of the transform...
Autores principales: | Kuo, Shu-Jui, Liu, Shan-Chi, Huang, Yuan-Li, Tsai, Chun-Hao, Fong, Yi-Chin, Hsu, Horng-Chaung, Tang, Chih-Hsin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628998/ https://www.ncbi.nlm.nih.gov/pubmed/31232696 http://dx.doi.org/10.18632/aging.102038 |
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