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A Warburg effect targeting vector designed to increase the uptake of compounds by cancer cells demonstrates glucose and hypoxia dependent uptake

Glycoconjugation to target the Warburg effect provides the potential to enhance selective uptake of anticancer or imaging agents by cancer cells. A Warburg effect targeting group, rationally designed to facilitate uptake by glucose transporters and promote cellular accumulation due to phosphorylatio...

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Detalles Bibliográficos
Autores principales: Glenister, Alexandra, Simone, Michela I., Hambley, Trevor W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629077/
https://www.ncbi.nlm.nih.gov/pubmed/31306426
http://dx.doi.org/10.1371/journal.pone.0217712