Substituted anthraquinones represent a potential scaffold for DNA methyltransferase 1-specific inhibitors

In humans, the most common epigenetic DNA modification is methylation of the 5-carbon of cytosines, predominantly in CpG dinucleotides. DNA methylation is an important epigenetic mark associated with gene repression. Disruption of the normal DNA methylation pattern is known to play a role in the ini...

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Detalles Bibliográficos
Autores principales: Switzer, Rebecca L., Medrano, Jessica, Reedel, David A., Weiss, Jill
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629088/
https://www.ncbi.nlm.nih.gov/pubmed/31306451
http://dx.doi.org/10.1371/journal.pone.0219830

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629088/
https://www.ncbi.nlm.nih.gov/pubmed/31306451
http://dx.doi.org/10.1371/journal.pone.0219830

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