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Lysyl oxidase–like 2 (LOXL2)–mediated cross-linking of tropoelastin
Lysyl oxidases (LOXs) play a central role in extracellular matrix remodeling during development and tumor growth and fibrosis through cross-linking of collagens and elastin. We have limited knowledge of the structure and substrate specificity of these secreted enzymes. LOXs share a conserved C-termi...
Autores principales: | Schmelzer, Christian E. H., Heinz, Andrea, Troilo, Helen, Lockhart-Cairns, Michael P., Jowitt, Thomas A., Marchand, Marion F., Bidault, Laurent, Bignon, Marine, Hedtke, Tobias, Barret, Alain, McConnell, James C., Sherratt, Michael J., Germain, Stéphane, Hulmes, David J. S., Baldock, Clair, Muller, Laurent |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Federation of American Societies for Experimental Biology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629125/ https://www.ncbi.nlm.nih.gov/pubmed/30676771 http://dx.doi.org/10.1096/fj.201801860RR |
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