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Clinical features and genetic characteristics of two Chinese pedigrees with fatal family insomnia

Background: Fatal familial insomnia (FFI) is a rare autosomal-dominant inherited prion disease characterized clinically by severe sleep disorder, motor signs, dysautonomia and abnormal behaviour. FFI is caused by a missense mutation at codon 178 of the prion protein gene (PRNP). Our study is aimed t...

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Detalles Bibliográficos
Autores principales:	He, Runcheng, Hu, Yacen, Yao, Lingyan, Tian, Yun, Zhou, Yafang, Yi, Fang, Zhou, Lin, Xu, Hongwei, Sun, Qiying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2019
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629183/ https://www.ncbi.nlm.nih.gov/pubmed/31122137 http://dx.doi.org/10.1080/19336896.2019.1617027

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